Benomyl (also marketed as Benlate) is a fungicide introduced in 1968 by DuPont. Thiophanate methyl is a systemic fungicide, usually applied as a dust or powder, used on vegetables, beans, nuts, potatoes, and turf. It is also employed as a casting worm control agent in amenity turf situations such as golf greens, tennis courts etc. EXTOXNET: The Extension Toxicology Network, methyl 1-[(butylamino) carbonyl]-H-benzimidazol-2-yl carbamate, chloroform 9.4 g/100 g; heptane 0.4 g/100g; ethanol 1 g/100g; acetone 5.3 g/100 g, decomposes without melting above 300 degrees C, negligible (< 5 x 10 to the minus 6 Pa) @ 25 degrees C. Reference List Number 10. Early events in benomyl toxicity include the physical sloughing of the apical third of the entire germinal epithelium, including the Sertoli cell cytoplasm and any attached germ cells. This reflects the interaction of colchicine with tubulin (which possesses a long τc and is responsible for the negative cross peaks; Clément et al., unpublished data).

Di Monte, in, Fitzmaurice et al., 2013, 2014; Tanner et al., 2011; van der Mark et al., 2014, Costello et al., 2009; Seidler et al., 1996; Semchuk et al., 1993; Wang et al., 2011, Reproductive and Developmental Toxicology (Second Edition), The major benzimidazole fungicides include, International Journal of Hygiene and Environmental Health. 1007 Market St. Wilmington, DE 19898 STATUS: General use. NPIC is open five days However, the maximization test conducted in the same study showed 2% benomyl to be a potent experimental allergen. Like Crk-II (Matsuda et al., 1994) and Ced-5 (Reichman et al., 1992), DCrk consists of one SH2 and two SH3 domains. In addition, DRac1 and Mbc have been linked genetically in the eye, in which loss of one copy of mbc suppresses the Drac1 overexpression phenotype (Nolan et al., 1998). Garthwaite, D.G., Thomas, M.R., Hart, M.J, and Wild, S, Outdoor vegetable crops in Great Britain 1995, Pesticide Usage Survey Report 134, Central Science Laboratory, 1997.

The orthologs of Mbc that have been examined in other systems appear to be involved in diverse processes that include cell engulfment, cell migration, epithelial morphogenesis and migration, and oncogenic transformation (Hasegawa et al., 1996; Wu and Horvitz, 1998). For English translation, see HYSAAV. This list is provided as an aid in reviewing pesticide data. Thiophanate, under the trade name Topsin, is effective against several root and foliage fungi affecting turf grasses and vegetable crops. [citation needed], Benomyl binds strongly to soil and does not dissolve in water to any great extent. In Drosophila, as in other organisms, the small GTPase Rac1 (Ras-related C3 botulinum toxin substrate) may function as a major target of the CDM family (Kiyokawa et al., 1998a, 1998b; Nolan et al., 1998; Albert et al., 2000; Reddien and Horvitz, 2000; Gumienny et al., 2001).

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